Autor: |
T. R. Hagadone, A. B. Miller, Michael S. Lajiness, Mark A. Johnson, Gerald M. Maggiora |
Rok vydání: |
1988 |
Předmět: |
|
Zdroj: |
Mathematical and Computer Modelling. 11:626-629 |
ISSN: |
0895-7177 |
DOI: |
10.1016/0895-7177(88)90568-7 |
Popis: |
Chemical databases are potential sources of structural and related information that may be of great value in the discovery and development of new medicinal agents. However, to utilize this information effectively requires sophisticated computer-based methods. An overview of methods appropriate to lead finding and optimization is presented, and a number of issues concerning their application are discussed. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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