Changes in Nutrition Impact Symptoms, Nutritional and Functional Status during Head and Neck Cancer Treatment
| Autor: | Norshariza Jamhuri, Zulfitri Azuan Mat Daud, Zuriati Ibrahim, Zalina Abu Zaid, May Kay Neoh, Zuwariah Abdul Rahman, Nor Baizura Md. Yusop |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty medicine.medical_treatment lcsh:TX341-641 malnutrition nutrition impact symptoms Article Body Mass Index Eating Young Adult 03 medical and health sciences Grip strength 0302 clinical medicine Weight loss Internal medicine Weight Loss medicine Humans Nutritional Physiological Phenomena Prospective Studies Aged Chemotherapy 030109 nutrition & dietetics Nutrition and Dietetics business.industry Head and neck cancer Middle Aged medicine.disease Radiation therapy nutritional status Malnutrition Nutrition Assessment Head and Neck Neoplasms 030220 oncology & carcinogenesis Dietary Supplements oral nutritional supplements Female Observational study head and neck cancer Nutrition Therapy medicine.symptom Energy Intake business dietary intake lcsh:Nutrition. Foods and food supply Body mass index Food Science |
| Zdroj: | Nutrients Volume 12 Issue 5 Nutrients, Vol 12, Iss 1225, p 1225 (2020) |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu12051225 |
| Popis: | Background: The purpose of this study is to evaluate changes in nutrition impact symptoms (NIS) and nutritional and functional status that occur throughout radiotherapy in head and neck cancer (HNC) patients. Methods: A prospective observational study of HNC inpatients who underwent radiotherapy with or without chemotherapy were recruited to participate. Fifty patients were followed for the periods before, in the middle and at the end of radiotherapy. Nutritional parameters were collected throughout radiotherapy. Results: According to Patient-Generated Subjective Global Assessment (PG-SGA), there was an increase from a baseline of 56% malnourished HNC patients to 100% malnourished with mean weight loss of 4.53 ± 0.41kg (7.39%) at the end of radiotherapy. Nutritional parameters such as muscle mass, fat mass, body mass index, dietary energy and protein intake decrease significantly (p < 0.0001) while NIS score, energy and protein intake from oral nutritional supplements (ONS) increased significantly (p < 0.0001). Hand grip strength did not differ significantly. All HNC patients experienced taste changes and dry mouth that required ONS at the end of treatment. ONS compliance affected the percentage of weight loss (p = 0.013). Conclusions: The intensive nutritional care time point was the middle of RT. The PG-SGA and NIS checklist are useful for monitoring nutrition for HNC patients. |
| Databáze: | OpenAIRE |
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