B-Type Natriuretic Peptides (BNP) and Tissue Doppler E/e´ Before and After 4 Weeks Standard Treatment of African Heart Failure Subjects: The ABU-BNP Longitudinal Survey

Autor: A. I. Oyati, Austine O Obasohan, Obiageli Uzoamaka Onyemelukwe, SS Danbauchi
Rok vydání: 2019
Předmět:
Male
Time Factors
Endocrinology
Diabetes and Metabolism

030204 cardiovascular system & hematology
left ventricular filling pressure
Severity of Illness Index
Ventricular Function
Left

0302 clinical medicine
Natriuretic Peptide
Brain

Medicine
Pharmacology (medical)
Longitudinal Studies
Prospective Studies
030212 general & internal medicine
Original Research
education.field_of_study
Ejection fraction
Standard treatment
before and after 4 weeks standard therapy
Hematology
General Medicine
Middle Aged
Treatment Outcome
B type natriuretic peptides
Cardiology
Mitral Valve
Female
Corrigendum
Cardiology and Cardiovascular Medicine
Adult
medicine.medical_specialty
Population
Diastole
Black People
Nigeria
pulsed tissue doppler
African heart failure
03 medical and health sciences
Predictive Value of Tests
Internal medicine
Humans
education
Echocardiography
Doppler
Pulsed

Heart Failure
business.industry
Public Health
Environmental and Occupational Health

Reproducibility of Results
Repeated measures design
medicine.disease
B-type natriuretic peptide
Heart failure
University teaching
business
Biomarkers
Zdroj: Vascular Health and Risk Management
ISSN: 1178-2048
DOI: 10.2147/vhrm.s211498
Popis: Background The study aimed at determining the response of BNP and tissue Doppler (TD) E/e´ to standard heart failure (HF) therapy in an African black population as data on these are lacking in Africa. BNP assessment in relation to HF severity and its association with its predictors were also determined. Methods It was a longitudinal-analytical study with a one month follow-up among 100 HF patients seen at Ahmadu Bello University Teaching Hospital, Zaria-Nigeria. Two-way Repeated Measures ANOVA determined BNP levels before and after treatment according to the HF severity. Wilcoxon-Signed Ranks test determined the difference in BNP and TD E/e´ before and after treatment. Pearson’s correlation assessed log-transformed BNP’s association with its predictors. Results BNP significantly (p
Databáze: OpenAIRE