The effect of alteration of nuclear lipids on messenger RNA transport from isolated nuclei
| Autor: | Atif B. Awad, Anthony Yannarell |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
chemistry.chemical_classification
Cell Nucleus Male Messenger RNA Degree of unsaturation Fatty Acids Biophysics Fatty acid Biological Transport Active Rats Inbred Strains Cell Biology Biology Lipid Metabolism Biochemistry Molecular biology Rats Cytosol chemistry Fatty Acids Unsaturated Animals Fatty acid composition RNA Messenger Molecular Biology Polyunsaturated fatty acid |
| Zdroj: | Biochemical and biophysical research communications. 108(3) |
| ISSN: | 0006-291X |
| Popis: | Studies were performed to examine the effect of alteration of the fatty acid composition of nuclear lipids on messenger RNA transport. Rats were maintained for four weeks on a semi-synthetic diet enriched in either saturated or polyunsaturated fatty acids. Messenger RNA transport was monitored by using a cell-free system comprised of isolated nuclei and fortified cytosol. This transport was found to be reduced by 34% from nuclei isolated from animals fed the diet enriched in saturated fatty acids as compared with the diet enriched in polyunsaturated fatty acids. The reduction was associated with a decrease in the unsaturation index of the nuclear fatty acids. |
| Databáze: | OpenAIRE |
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