Cyclosulfamide as a chiral auxiliary: application to efficient asymmetric synthesis (alkylation/aldolization)
| Autor: | Gérald Lopez, Fabien Fécourt, Jean Martinez, Arie van der Lee, Georges Dewynter |
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| Přispěvatelé: | Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Institut Européen des membranes (IEM), Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM) |
| Rok vydání: | 2010 |
| Předmět: |
Chiral auxiliary
[CHIM.ORGA]Chemical Sciences/Organic chemistry 010405 organic chemistry Chemistry Stereochemistry Organic Chemistry Chiral ligand Enantioselective synthesis Alkylation 010402 general chemistry 01 natural sciences Catalysis 0104 chemical sciences Inorganic Chemistry chemistry.chemical_compound [CHIM.CRIS]Chemical Sciences/Cristallography Physical and Theoretical Chemistry |
| Zdroj: | Tetrahedron: Asymmetry Tetrahedron: Asymmetry, Elsevier, 2010, 21, pp.2361-2366. ⟨10.1016/j.tetasy.2010.09.001⟩ |
| ISSN: | 0957-4166 |
| DOI: | 10.1016/j.tetasy.2010.09.001 |
| Popis: | The chiral cyclosulfamide (S)-2-benzyl-4-isopropyl-1,2,5-thiadiazolidine 1,1-dioxide was designed as a chimera of Evans and Oppolzer chiral auxiliaries. The N-propionyl derivative appeared to be very powerful for the stereocontrolled synthesis of chiral building blocks through asymmetric aldolization and alkylation reactions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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