Volume and Composition of Emboli in Neuroprotected Stenting of the Carotid Artery
| Autor: | E. Rafel, Pilar Piñero, E. Martínez, J.R. Gonzalez-Marcos, Antonio Mayol, Alberto Gil-Peralta, Francisco Moniche, Alejandro González, Aurelio Cayuela |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Blood Platelets Male medicine.medical_specialty medicine.medical_treatment medicine.artery Angioplasty medicine Humans Carotid Stenosis Radiology Nuclear Medicine and imaging Prospective Studies Embolization Stroke Aged Aged 80 and over Fibrin Interventional business.industry Middle Aged medicine.disease Institutional review board Stenosis Balloon dilations Intracranial Embolism Female Stents Neurology (clinical) Radiology Internal carotid artery business Angioplasty Balloon Carotid Artery Internal Filtration Volume (compression) |
| Zdroj: | AJNR Am J Neuroradiol |
| ISSN: | 1936-959X 0195-6108 |
| DOI: | 10.3174/ajnr.a1407 |
| Popis: | BACKGROUND AND PURPOSE: Periprocedural microembolization is a major and permanent risk for patients treated by angioplasty and stent placement of high-grade carotid stenoses. Little is known however about the characteristics and significance of these embolized particles. Our aim was to assess the volume and composition of debris captured by filters during carotid angioplasty and stent placement (CAS) of severe internal carotid artery (ICA) stenoses. MATERIALS AND METHODS: Institutional review board approval and informed consent from all subjects were obtained. Two hundred one patients (mean age, 66.2 years; range, 35–82 years) with ≥70% stenosis of the ICA underwent filter-protected CAS. Ultrastructural and semiquantitative analysis of the volume of filters was obtained. Multifactorial statistical analysis was performed to determine factors related to debris volume and composition. RESULTS: Transient ischemic attack occurred in 6 patients (3%), and a major stroke, in 1 (0.5%). Debris was found in 117 filters (58.2%), with volume |
| Databáze: | OpenAIRE |
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