Intravascular Lithotripsy as a Novel Treatment Method for Calcified Unprotected Left Main Diseases—Comparison to Rotational Atherectomy—Short-Term Outcomes
| Autor: | Piotr Rola, Jan Jakub Kulczycki, Adrian Włodarczak, Mateusz Barycki, Szymon Włodarczak, Marek Szudrowicz, Łukasz Furtan, Artur Jastrzębski, Maciej Pęcherzewski, Maciej Lesiak, Adrian Doroszko |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Atherectomy
Coronary Percutaneous Coronary Intervention Treatment Outcome Health Toxicology and Mutagenesis Lithotripsy Public Health Environmental and Occupational Health Humans left main rotational atherectomy intravascular lithotripsy high-risk percutaneous coronary intervention percutaneous coronary intervention (PCI) vascular disease coronary artery diseases (CAD) cardiovascular diseases shock wave intravascular lithotripsy device Coronary Artery Disease Vascular Calcification Retrospective Studies |
| Zdroj: | International Journal of Environmental Research and Public Health; Volume 19; Issue 15; Pages: 9011 |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph19159011 |
| Popis: | Background: The unprotected calcified Left Main disease represents a high-risk subset for percutaneous coronary intervention (PCI), and it is associated with a higher number of periprocedural complications and an increased rate of in-stent thrombosis and restenosis. Adequate lesion preparation plays a crucial role in achieving a favorable PCI outcome. Rotational Atherectomy (RA) is a well-established plaque-modifying method; nevertheless, the data regarding the effectiveness of RA in LM diseases is scarce. Recently, the novel ShockWave-Intravascular-Lithotripsy(S-IVL) device has been introduced to the PCI armamentarium in order to modify the calcified plaque. Methods: We performed a retrospective evaluation of 44 consecutive subjects who underwent the LM-PCI, and who were supported by either the RA or S-IVL. Results: The Rota group consisted of 29 patients with a mean syntax score of 28.0 ± 7.5. The S-IVL group was composed of 15 subjects with a syntax score of 23.3 ± 13.0 There were no statistical differences regarding MACE between the RA and Shockwave arms of the in-hospital group (10.3% vs. 6.7%), or in the six month (17.2% vs. 13.3%) follow-up group. Conclusions: RA and S-IVL could be safe and effective therapeutic strategies for calcified LM disease. Further studies with a higher number of participants and longer follow-up times are warranted to establish the potential benefits of RA and S-IVL for the management of LM stenosis. |
| Databáze: | OpenAIRE |
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