Radiotherapy as an integrated part of the treatment of soft tissue sarcomas
| Autor: | A.M. Mandard, N. Boulier, A. Busson, Abbatucci Js, J. de Ranieri, A. Tanguy |
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| Rok vydání: | 1984 |
| Předmět: |
Male
medicine.medical_specialty business.industry medicine.medical_treatment Soft tissue Sarcoma Soft Tissue Neoplasms Hematology Disease Long term results Middle Aged Prognosis Surgery Natural history Clinical trial Radiation therapy Oncology Treatment Schedule medicine Humans Radiology Nuclear Medicine and imaging Female Neoplasm Recurrence Local business |
| Zdroj: | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2(2) |
| ISSN: | 0167-8140 |
| Popis: | Summary A considerable improvement in the prognosis of soft tissue sarcomas in the adult has been obtained with a treatment schedule combining surgery and routine radiation therapy (possibly preoperative and certainly postoperative); local recurrences, the predominant element in the natural history of the disease, have become very rare and limb function is generally maintained. Metastatic risk presents the major problem, and in our series spread of the disease remained uncontrolled in 25% of cases. Further research is required in this area, and a better definition of the risk factors, especially with regard to histology, is needed. We suggest that the possibility of reinforcing treatment of those histological forms at high metastatic risk by the introduction of multidrug therapy after local treatment be investigated. Such studies can only be effectively conducted within the framework of a multicenter collaborative controlled clinical trial. |
| Databáze: | OpenAIRE |
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