Frequency and Pattern of Noninfectious Adverse Transfusion Reactions at a Tertiary Care Hospital in Korea
| Autor: | Jooyoung Cho, Sinyoung Kim, Hyun Ok Kim, Essam Alghamdi, Seung Jun Choi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Blood transfusion medicine.medical_treatment Clinical Biochemistry 030204 cardiovascular system & hematology Tertiary Care Centers 03 medical and health sciences 0302 clinical medicine Internal medicine Republic of Korea Blood plasma medicine Humans Blood Transfusion Platelet Febrile non-hemolytic transfusion reaction Adverse effect Retrospective Studies Transfusion Medicine business.industry Biochemistry (medical) Adverse transfusion reaction Allergic reaction Transfusion Reaction Retrospective cohort study General Medicine Tertiary care hospital medicine.disease Transfusion reporting system 030220 oncology & carcinogenesis Immunology Fresh frozen Original Article business |
| Zdroj: | Annals of Laboratory Medicine |
| ISSN: | 2234-3814 2234-3806 |
| DOI: | 10.3343/alm.2016.36.1.36 |
| Popis: | Background Although transfusion is a paramount life-saving therapy, there are multiple potential significant risks. Therefore, all adverse transfusion reaction (ATR) episodes require close monitoring. Using the computerized reporting system, we assessed the frequency and pattern of non-infectious ATRs. Methods We analyzed two-year transfusion data from electronic medical records retrospectively. From March 2013 to February 2015, 364,569 units of blood were transfused. Of them, 334,582 (91.8%) records were identified from electronic nursing records. For the confirmation of ATRs by blood bank physicians, patients' electronic medical records were further evaluated. Results According to the nursing records, the frequency of all possible transfusion-related events was 3.1%. After the blood bank physicians' review, the frequency was found to be 1.2%. The overall frequency of febrile non-hemolytic transfusion reactions (FNHTRs) to red blood cells (RBCs), platelet (PLT) components, and fresh frozen plasmas (FFPs) were 0.9%, 0.3%, and 0.2%, respectively, and allergic reactions represented 0.3% (RBCs), 0.9% (PLTs), and 0.9% (FFPs), respectively. The pre-storage leukocyte reduction significantly decreased the frequency of FNHTRs during the transfusion of RBCs (P |
| Databáze: | OpenAIRE |
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