Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles

Autor:	Nicolai A. Aksenov, Alexander V. Aksenov, Lidiya A. Prityko, Dmitrii A. Aksenov, Daria S. Aksenova, Mezvah A. Nobi, Michael Rubin
Rok vydání:	2022
Předmět:	General Chemical Engineering General Chemistry
Zdroj:	ACS omega. 7(16)
ISSN:	2470-1343
Popis:	A facile and highly efficient method for the preparation of 2-(3-oxoindolin-2-ylidene)acetonitriles from 4-(2-aminophenyl)-4-oxo-2-phenylbutanenitriles is described. The featured transformation operates via nucleophilic intramolecular cyclization and involves oxidation of the aniline moiety. Overall, this modification allowed for the improvement of yields and expansion of the reaction scope.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2320d04e44cf9fd750ea1e2db5dcd247 https://pubmed.ncbi.nlm.nih.gov/35573208 Zobrazit plný text záznamu