Heritable Gut Microbiome Associated with Salmonella enterica Serovar Pullorum Infection in Chickens
| Autor: | Hao Zhou, Ke Xu, Han Chengxiao, Huaixi Luo, Fisayo T. Akinyemi, Zheng Yuming, Qizhong Huang, Jinmei Ding, He Meng, Kaixuan Yang, Zhenxiang Zhou, Caiju Gu, Lingxiao Luo, Chao Qin, Chuan He, Lingyu Yang, Xiao Lu |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Serotype
animal structures Physiology Offspring Biovar animal diseases chicken Gut flora Biochemistry Microbiology digestive system Host-Microbe Biology Salmonella Pullorum 03 medical and health sciences Genetics Microbiome Molecular Biology Gene Ecology Evolution Behavior and Systematics host genetic variants 030304 developmental biology 0303 health sciences biology gut microbiota Host (biology) digestive oral and skin physiology 0402 animal and dairy science mGWAS 04 agricultural and veterinary sciences heritable biology.organism_classification 040201 dairy & animal science QR1-502 Computer Science Applications Salmonella enterica Modeling and Simulation embryonic structures Research Article |
| Zdroj: | mSystems mSystems, Vol 6, Iss 1 (2021) |
| ISSN: | 2379-5077 |
| Popis: | The present study investigated the association among the host genome, the gut microbiome, and S. Pullorum infection in chickens. The results suggested that the gut microbial structure is altered in S. Pullorum-infected chickens. Pullorum disease is one of the most common diarrhea-related diseases caused by Salmonella enterica subspecies enterica serovar Gallinarum biovar Pullorum (S. Pullorum); it negatively affects the poultry industry. However, limited studies have explored the association between the gut microbiota and S. Pullorum infection in chickens. In the present study, we performed a microbiome comparison and a microbiome genome-wide association study (mGWAS) to investigate the association among the host genetics, the gut microbiota, and pullorum disease in chickens. We found that S. Pullorum infection in chickens could alter the abundance of 39 bacterial genera (P |
| Databáze: | OpenAIRE |
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