Driving Performance of Depressed Patients who are Untreated or Receive Long-Term Antidepressant (SSRI/SNRI) Treatment
| Autor: | Johannes G. Ramaekers, Stefan Jongen, Frederick Vinckenbosch, Annemiek Vermeeren, Marleen Wingen, Nick N. J. J. M. van der Sluiszen |
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| Přispěvatelé: | RS: FPN NPPP II, Section Psychopharmacology, RS: FSE MSP |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male DISORDER medicine.medical_specialty Automobile Driving PSYCHOMOTOR FUNCTION medicine.drug_class Mirtazapine Poison control ROAD-TRAFFIC ACCIDENTS ALCOHOL 03 medical and health sciences Benzodiazepines Young Adult 0302 clinical medicine MIRTAZAPINE Rating scale Internal medicine DRIVERS medicine Journal Article Humans Pharmacology (medical) long-term treatment Psychiatry Depression (differential diagnoses) Psychomotor function Benzodiazepine driving performance General Medicine IMPAIRMENT Antidepressive Agents 030227 psychiatry Psychiatry and Mental health antidepressants YOUNG depression Antidepressant Drug Therapy Combination Female Psychology Reuptake inhibitor OUTPATIENTS 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Pharmacopsychiatry, 50(5), 182-188. Georg Thieme Verlag |
| ISSN: | 0176-3679 |
| Popis: | Introduction Depression is a mental disorder likely to affect everyday functions. The present study aimed to assess actual driving performance of depressed patients who were without specific antidepressant treatment or received long-term antidepressant treatment. Methods A standardized on-the-road driving test was used to assess standard deviation of lateral position (SDLP) in 3 patient groups receiving either no antidepressant treatment (with or without benzodiazepine medication) or treatment with selective serotonin/noradrenalin reuptake inhibitors for a period of 6–52 weeks. Severity of depression was assessed using Beck’s Depression Inventory and the Hamilton Depression Rating Scale. The performance of patient groups was compared to healthy controls. Results The mean SDLP of untreated and treated patients was significantly higher than that of healthy controls. Driving impairment in the long-term treated group was significantly less than in the untreated groups. SDLP was positively correlated to severity of depression across all groups. Discussion It is concluded that symptoms of depression are a major cause of driving impairment. Reductions in severity of depression through antidepressant treatment reduce severity of driving impairment. |
| Databáze: | OpenAIRE |
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