The effects of microgravity on the digestive system and the new insights it brings to the life sciences
| Autor: | Jia-Qi Yang, Jin‑Lian Zhou, Zheng‑Yang Chen, Sheng Yu Lu, Song Guo, Jian Wu Yang, Hong-Wei Sun, Shao Bin Chai, Zheng Peng Li, Nan Jiang, Yan Cui, He‑Ming Yang, Tao Zhang, Hong‑Feng Yan, Pei Ming Sun, Binbin Li |
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| Rok vydání: | 2020 |
| Předmět: |
010504 meteorology & atmospheric sciences
Computer science Health Toxicology and Mutagenesis 01 natural sciences Space exploration Biological Science Disciplines 0103 physical sciences Animals Humans 010303 astronomy & astrophysics 0105 earth and related environmental sciences Radiation Ecology Weightlessness Mechanism (biology) Astronomy and Astrophysics Ideation Space Flight Agricultural and Biological Sciences (miscellaneous) On cells Risk analysis (engineering) Simulated microgravity Astronauts Medical science Digestive System Space environment |
| Zdroj: | Life sciences in space research. 27 |
| ISSN: | 2214-5532 |
| Popis: | Background Weightlessness is a component of the complex space environment. It exerts adverse effects on the human body, and may pose unknown challenges to the implementation of space missions. The regular function of the digestive system is an important checkpoint for astronauts to conduct missions. Simulated microgravity can recreate the changes experienced by the human body in a weightless environment in space to a certain extent, providing technical support for the exploration of its mechanism and a practical method for other scientific research. Methods and materials In the present study, we reviewed and discussed the latest research on the effects of weightlessness or simulated microgravity on the digestive system, as well as the current challenges and future expectations for progress in medical science and further space exploration. Results A series of studies have investigated the effects of weightlessness on the human digestive system. On one hand, weightlessness and the changing space environment may exert certain adverse effects on the human body. Studies based on cells or animals have demonstrated the complex effects on the human digestive system in response to weightlessness. On the other hand, a microgravity environment also facilitates the ideation of novel concepts for research in the domain of life science. Conclusion The effects of weightlessness on the digestive system are considerably complicated. The emergence of methods that help simulate a weightless environment provides a more convenient alternative for assessing the impact and the mechanism underlying the effect of weightlessness on the human body. In addition, the simulated microgravity environment facilitates the ideation of novel concepts for application in regenerative medicine and other fields of life science. |
| Databáze: | OpenAIRE |
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