Chronic and acute infection of the gall bladder by Salmonella Typhi: understanding the carrier state
| Autor: | Joanna M. Marshall, Geoffrey Gonzalez-Escobedo, John S. Gunn |
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| Rok vydání: | 2010 |
| Předmět: |
Serotype
Salmonella Gallbladder Diseases Disease Biology Salmonella typhi medicine.disease_cause Microbiology Article Typhoid fever medicine Animals Humans Gall General Immunology and Microbiology Carrier state medicine.disease biology.organism_classification digestive system diseases Disease Models Animal Infectious Diseases Salmonella enterica Biofilms Carrier State Salmonella Infections Immunology |
| Zdroj: | Nature Reviews Microbiology. 9:9-14 |
| ISSN: | 1740-1534 1740-1526 |
| DOI: | 10.1038/nrmicro2490 |
| Popis: | Despite major treatment and prevention efforts, millions of new typhoid infections occur worldwide each year. For a subset of infected individuals, Salmonella enterica subsp. enterica serovar Typhi colonizes the gall bladder and remains there long after symptoms subside, serving as a reservoir for the further spread of the disease. In this Progress article, we explore recent advances in our understanding of the mechanisms by which Salmonella spp. — predominantly S. Typhi — colonize and persist in the human gall bladder. |
| Databáze: | OpenAIRE |
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