Non-Paraneoplastic Related Retinopathy: clinical challenges and review
| Autor: | Vitor K. L. Takahashi, Stephen H. Tsang, Christine L. Xu, Júlia T. Takiuti, Ruben Jauregui |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
business.industry Treatment regimen Progressive visual loss medicine.disease Malignancy Autoimmune retinopathy Dermatology Diagnosis of exclusion Article Autoimmune Diseases Ophthalmology Retinal Diseases Pediatrics Perinatology and Child Health Medicine Animals Humans business Genetics (clinical) Retinopathy |
| Zdroj: | Ophthalmic Genet |
| Popis: | Autoimmune retinopathy (AIR) is a rare inflammatory condition characterized by progressive visual loss, abnormalities in visual fields and electroretinographic exams, along with presence of circulating anti-retinal antibodies. There are two main forms of AIR: paraneoplastic AIR (pAIR) and presumed non-paraneoplastic AIR (npAIR). NpAIR is considered a diagnosis of exclusion, since it is typically made after other causes of retinopathy have been investigated and the absence of malignancy is confirmed. Work-up of a npAIR case is challenging since there are no standartizaded protocols for diagnosis and treatment. The treatment regimen may vary from case to case, and it can be best guided by a set of parameters including electrophysiological responses, visual outcomes, and presence of anti-retinal antibodies. The purpose of this review is to summarize the principal clinical features, investigation, and management of npAIR. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|