| Autor: |
Paluku Bahwere, Michèle Wilmet-Dramaix, Philippe Donnen, Maimouna Doudou Halidou, Daouda Alhousseini Maiga, Katia Castetbon, Salimata Wade, Mahaman Elhadji Hallarou, Mahamane Laouali Manzo |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| DOI: |
10.5281/zenodo.5533092 |
| Popis: |
Each year in Niger, more than 40% of children under 5 years suffer from chronic malnutrition and more than 10% from acute malnutrition. The national nutrition rehabilitation protocol encourages the use of local foods. The objective of this work is to analyze the impact of supplementation inMoringa oleifera.We conducted a randomized double-blind clinical trial in 400 children with moderate acute malnutrition (MAM) aged 6 to 59 months admitted to outpatient nutritional recovery centers (CRENAM). The children were divided into two groups; one group received Ready-to-Use Supplemental Foods (RUSF) and dry leaf powder fromMoringaoleiferaand the other group received RUSF and placebo. We did not find any difference on average weight gain between the two groups or on mid-upper arm circumference and size. The median length of stay in CRENAM was 5 and 4 weeks forMoringaand placebo respectively, with no statistical difference (P=0.522). The cure rate was 82% (2.72) in theMoringagroup with a RR of 1.03 (0.94 to 1.13) slightly in favor ofMoringa. Renal and hepatic toxicity ofMoringawas not observed. From this clinical trial, it could be held thatMoringasupplementation, despite the presence of nutritional indices in favor ofMoringa, does not have a significant effect on the nutritional recovery of MAM children but thatMoringahas no renal or hepatic toxicity. Supplementation in subjects already on dietetic treatment, dose reduced to minimum and duration of supplementation seems to have played a role in this absence of effect ofMoringa. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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