Physical exercise and epicardial adipose tissue: A systematic review and meta‐analysis of randomized controlled trials

Autor: Alejandro Lucia, Luis M. Ruilope, Pedro L. Valenzuela, Miguel León‐Sanz, Joaquín Arenas, Gonzalo Saco-Ledo, Adrián Castillo-García
Rok vydání: 2020
Předmět:
Zdroj: Obesity Reviews. 22
ISSN: 1467-789X
1467-7881
Popis: We performed a meta-analysis of the effects of exercise on epicardial adipose tissue (EAT). A systematic search was conducted in PubMed and Scopus (since inception to 1 February 2020) of randomized controlled trials assessing the effects of exercise interventions alone (with no concomitant weight loss intervention) on EAT. The standardized mean difference (Hedges' g) and 95% confidence interval between interventions were computed using a random effects model. Ten studies (including 521 participants who had, on average, overweight/obesity) met all inclusion criteria. Interventions were supervised and lasted 2 to 16 weeks (≥3 sessions·per week). Exercise significantly reduced EAT (g = 0.82 [0.57-1.07]) irrespective of the duration of the intervention or the EAT imaging assessment method. Exercise benefits were separately confirmed for endurance (six studies, n = 287; g = 0.83 [0.52-1.15]) but not for resistance exercise training (due to insufficient data for quantitative synthesis). It was not possible to compare the effect of high-intensity interval training (HIIT) versus moderate-intensity continuous training (two studies, one reporting higher benefits with HIIT and the other no differences). Physical exercise interventions-particularly endurance training, with further evidence needed for other exercise modalities-appear as an effective strategy for reducing EAT in individuals with overweight/obesity, which supports their implementation for cardiovascular risk reduction. Sin financiación 10.867 JCR (2021) Q1, 9/146 Endocrinology & Metabolism 2.536 SJR (2021) Q1,12/240 Endocrinology, Diabetes and Metabolism No data IDR 2021 UEM
Databáze: OpenAIRE
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