The Zika virus and pregnancy: evidence, management, and prevention
| Autor: | Devika Maulik, Ayse Citil Dogan, Dotun Ogunyemi, Santosh K. Kulkharni, Samuel T. Bauer, Christopher F Carpenter, Ray O. Bahado-Singh, Sandra Wayne |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty 030231 tropical medicine Guidelines as Topic Zika virus Miscarriage Fetal Development 03 medical and health sciences 0302 clinical medicine Aedes Pregnancy medicine ZikV Infection Animals Humans 030212 general & internal medicine Pregnancy Complications Infectious Intensive care medicine Travel biology Zika Virus Infection business.industry Infant Newborn Insect Bites and Stings Obstetrics and Gynecology Zika Virus biology.organism_classification medicine.disease Virology Infectious Disease Transmission Vertical Pediatrics Perinatology and Child Health Microcephaly Female business |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 30:386-396 |
| ISSN: | 1476-4954 1476-7058 |
| DOI: | 10.3109/14767058.2016.1174210 |
| Popis: | To comprehensively review the available evidence and existing consensus reports and guidelines regarding the pregnancy and reproductive implications of the mosquito-transmitted Zika virus (ZIKV) infection. A primary focus was to provide pertinent information to aid clinicians in the management of pregnancies at risk for, exposed to, or with confirmed ZIKV infection.An extensive literature review was performed using Pubmed. Practice guidelines and consensus reports were accessed from international, national, and professional organizations' websites. The clinical articles for ZIKV infection testing varied from case reports to small epidemiologic studies.A ZIKV epidemic has been declared in several countries in the Americas. Fifty-two travel-associated ZIKV infection cases have been reported throughout the USA (as of February 10, 2016). The consequences of congenital fetal/newborn ZIKV infection could potentially have devastating consequences including miscarriage, fetal death, and major anomalies such as microcephaly, brain and brain-stem defects, and long-term neurologic sequelae. While not definitive, current evidence suggests the existence of nonvector-borne transmission through sexual activity with an infected male partner. For women at risk for sexual transmission, condom use is advised, especially during pregnancy.While ZIKV infection appears to be a mild disease in the general population the potential consequences to the fetus and newborn could be profound. Management guidelines are currently evolving and will be significantly impacted as new evidence develops. It is therefore imperative that obstetric health-care providers keep abreast of this rapidly evolving information landscape that has so far characterized this outbreak. |
| Databáze: | OpenAIRE |
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