4-Bis(methylthio)methylene-2-phenyloxazol-5-one: versatile template for synthesis of 2-phenyl-4,5-functionalized oxazoles

Autor:	Nimesh C. Misra, Hiriyakkanavar Ila
Rok vydání:	2010
Předmět:	Spectrometry Mass Electrospray Ionization Magnetic Resonance Spectroscopy Organic Chemistry Chemical synthesis Combinatorial chemistry Adduct Oxazolone chemistry.chemical_compound chemistry Nucleophile Cyclization Surface modification Organic chemistry Methylene Oxazoles Silver carbonate
Zdroj:	The Journal of organic chemistry. 75(15)
ISSN:	1520-6904
Popis:	4-Bis(methylthio)methylene-2-phenyloxazol-5-one has been shown to be a versatile template for the synthesis of various 2-phenyl-3,4-substituted oxazoles via nucleophilic ring-opening of oxazolone with various oxygen, nitrogen, and carbon nucleophiles and subsequent 5-endo cyclization of the resulting acyclic adducts in the presence of silver carbonate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f5518feb4a90418de2f81675ac7d4a https://pubmed.ncbi.nlm.nih.gov/20670028 Zobrazit plný text záznamu