Acute severe pancreatitis in falciparum malaria
Autor: | Mrinal Kanti Taye, Bikash Narayan Choudhury, Dilip Kumar Saloi |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
Falciparum
medicine.medical_specialty Pathology Blood transfusion medicine.medical_treatment Ischemia malaria pancreatitis lcsh:Medicine Gastroenterology Internal medicine parasitic diseases medicine Hypoalbuminemia Leukocytosis biology treatment business.industry lcsh:R Metabolic acidosis Plasmodium falciparum General Medicine medicine.disease biology.organism_classification infection Pancreatitis prognosis medicine.symptom business Malaria |
Zdroj: | Medical Journal of Dr. D.Y. Patil University, Vol 9, Iss 4, Pp 512-514 (2016) |
ISSN: | 0975-2870 |
Popis: | Though different organs have been involved in falciparum malaria, pancreas has not been a common organ involved so far. Pancreatitis is a rare complication of Plasmodium falciparum malaria. The patient was admitted with low Glasgow Coma Scale and was febrile and in hypotension, and with oral bleeding. Preliminary investigations revealed leukocytosis, severe anemia, low platelet count, abnormal renal function test, deranged liver enzymes with conjugated hyperbilirubinemia, raised international normalized ratio, and hypoalbuminemia. Arterial blood gas showed metabolic acidosis. The raised pancreatic enzymes with radiological evidence of pancreatitis helped establish the diagnosis. Patient's condition improved with antimalarial, blood transfusion, circulatory support, and hemodialysis. The most possible mechanism of pancreatitis in malaria is microvascular occlusion with resultant ischemia, activation of pancreatic enzymes, and injury to pancreas due to autodigestion. Prognosis was good in our case of malarial pancreatitis. |
Databáze: | OpenAIRE |
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