THE STUDY OF THE INNATE AND ACQUIRED CELLULAR IMMUNITY CHAINS INDICATORS IN THE PERIPHERAL BLOOD OF PATIENTS WITH HIV INFECTION
| Autor: | L B Kalnina, L M Selimova, L V Serebrovskaya, Ivanova La, D N Nosik |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
CD4-Positive T-Lymphocytes
Cellular immunity CD4-CD8 Ratio Human immunodeficiency virus (HIV) HIV Infections Adaptive Immunity CD8-Positive T-Lymphocytes medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Antiretroviral Therapy Highly Active medicine Antiretroviral treatment Humans Immunity Cellular business.industry Monocyte Biochemistry (medical) General Medicine Acquired immune system Peripheral blood Medical Laboratory Technology medicine.anatomical_structure Immunology business CD8 After treatment 030215 immunology |
| Zdroj: | Russian Clinical Laboratory Diagnostics. 65:24-28 |
| ISSN: | 0869-2084 |
| DOI: | 10.18821/0869-2084-2020-65-1-24-28 |
| Popis: | In this study was made an attempt to reveal additional laboratory markers of white blood for preliminary estimation level of HIV-infection development. Essentially such markers these are in progress without complex equipment and expensive reagent. It was studied alterations of basic values cells of innate and acquired immunity of peripheral blood HIV-infected individuals with and without antiretroviral treatment (ART) during infection. It was estimate value leukocytes, neutrophils, monocytes, lymhpocytes, T-lymhpocytes, CD4+, CD8+ T-cells, CD4/CD8 index. It was used the first analysis in the time of registration for regular medical check-up and the intermediate derived during 2017-2018 years. Patients without ART and with ART before and after treatment had rates of leukocytes, lymhpocytes, T-lymhpocytes, monocytes and neutrophils within the normal guideline. Essential changes were observed in basic conventional laboratory parameters evaluation of HIV-infection dynamic (parameters of CD4+and CD8+ cells, CD4/CD8 index). Thereby it was impossible to reveal supplementary immunological markers of HIV-infection. |
| Databáze: | OpenAIRE |
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