Association between number of teeth and Alzheimer’s disease using the National Database of Health Insurance Claims and Specific Health Checkups of Japan

Autor: Takeyuki Yamaguchi, Midori Tsuneishi, Tatsuo Yamamoto, Tsuyoshi Kodama, Tamotsu Sato
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Molar
Male
Teeth
Databases
Factual
Dentistry
Disease
Logistic regression
Alzheimer's Disease
Geographical Locations
Medical Conditions
Oral Diseases
Japan
Medicine and Health Sciences
Cognitive Impairment
Aged
80 and over
Multidisciplinary
Cognitive Neurology
Diagnosis
Oral
Neurodegenerative Diseases
Middle Aged
Neurology
Alzheimer's Disease Diagnosis and Management
Medicine
Female
Anatomy
Research Article
Asia
Science
Cognitive Neuroscience
Oral Medicine
Insurance Claim Review
Tooth Loss
stomatognathic system
Diagnostic Medicine
Alzheimer Disease
Mental Health and Psychiatry
medicine
Health insurance
Humans
Periodontitis
Periodontal Diseases
Aged
Insurance
Health
business.industry
Biology and Life Sciences
Odds ratio
medicine.disease
Confidence interval
stomatognathic diseases
Logistic Models
Jaw
Age Groups
People and Places
Cognitive Science
National database
Dementia
Population Groupings
business
Digestive System
Head
Neuroscience
Zdroj: PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0251056 (2021)
ISSN: 1932-6203
Popis: Associations of numbers of teeth present and of missing teeth with Alzheimer’s disease were cross-sectionally analyzed using the National Database of Health Insurance Claims and Specific Health Checkups of Japan. Dental care claims data of patients aged 60 years or older diagnosed with periodontitis (n = 4,009,345) or missing teeth (n = 662,182) were used to obtain information about the numbers of teeth present and of missing teeth, respectively, and they were combined with medical care claims data including the diagnosis of Alzheimer’s disease. Numbers of teeth present and of missing teeth excluding third molars were calculated using the dental formula in the claims for periodontitis and missing teeth, respectively, and categorized into three groups each. Percentages of subjects treated for Alzheimer’s disease with 20–28, 10–19, and 1–9 teeth present were 1.95%, 3.87%, and 6.86%, respectively, in patients diagnosed as having periodontitis, and those treated for Alzheimer’s disease with 1–13, 14–27, and 28 missing teeth were 2.67%, 5.51%, and 8.70%, respectively, in patients diagnosed as having missing teeth. Logistic regression models using treatment for Alzheimer’s disease as an outcome variable and adjusting for age and sex showed that odds ratios (95% confidence intervals) for patients with 10–19 and 1–9 teeth (reference: 20–28 teeth) were 1.11 (1.10–1.13) and 1.34 (1.32–1.37), respectively, (pp
Databáze: OpenAIRE
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