Fasting serum triglyceride and high-density lipoprotein cholesterol levels in patients intended to be treated for dyslipidemia
| Autor: | Katherine K. Anagnostopoulou, Genovefa Kolovou, Helen Bilianou, Ilias Petropoulos, Klelia D. Salpea, Nektarios D. Pilatis, Dennis V. Cokkinos, Ioannis S. Hoursalas |
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| Rok vydání: | 2005 |
| Předmět: |
Male
lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_specialty Endocrinology Diabetes and Metabolism Population Cohort Studies chemistry.chemical_compound High-density lipoprotein high-density lipoprotein cholesterol Internal medicine Total cholesterol medicine Humans Pharmacology (medical) In patient Inverse correlation education triglycerides Original Research Dyslipidemias Hypolipidemic Agents education.field_of_study Triglyceride Cholesterol business.industry dyslipidemia Cholesterol HDL Public Health Environmental and Occupational Health Fasting Hematology General Medicine Middle Aged medicine.disease Endocrinology chemistry lcsh:RC666-701 Female lipids (amino acids peptides and proteins) Cardiology and Cardiovascular Medicine business Dyslipidemia |
| Zdroj: | Vascular Health and Risk Management, Vol Volume 1, Pp 155-161 (2005) Vascular Health and Risk Management |
| ISSN: | 1176-6344 |
| DOI: | 10.2147/vhrm.1.2.155.64079 |
| Popis: | Genovefa D Kolovou1, Katherine Anagnostopoulou1, Nektarios D Pilatis1, Klelia D Salpea1, Ioannis S Hoursalas1, Ilias Petropoulos1, Helen I Bilianou2, Dennis V Cokkinos11Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece; 2Cardiology Department, Tzanio State Hospital, Piraeus, GreeceObjective: The aim of the present investigation was to evaluate the influence of serum triglycerides (TG) on other plasma lipids in patients to be treated for dyslipidemia.Methodology: Lipid profiles of a cohort of 801 patients (487 males and 314 females) aged 57 ± 9 years (mean ± SD) were evaluated. Patients were stratified according to their plasma lipid levels. They were divided into various groups on the basis of serum TG (≥ 150 or < 150 mg/dL) and high-density lipoprotein cholesterol (HDL-C) (≥ 40 or < 40 mg/dL).Results: Patients with TG ≥ 150 mg/dL had a higher total cholesterol and lower HDL-C levels compared with those with TG < 150 mg/dL, (p < 0.001). Patients with HDL-C < 40 mg/dL had a lower serum total cholesterol and higher TG compared with those with HDL-C ≥ 40 mg/dL (p = 0.011 and p < 0.0001, respectively). In all patients as well as in the subgroups, an inverse correlation between TG and HDL-C was found (r = –0.377, p < 0.001).Conclusions: Although, the metabolic pathway for TG and HDL-C is closely linked, an inverse correlation between TG and HDL-C levels seems to exist in the entire sampled population. This correlation also appears to persist in fasting patients with low levels of TG.Keywords: triglycerides, high-density lipoprotein cholesterol, dyslipidemia |
| Databáze: | OpenAIRE |
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