The use of evolutionary biology concepts for genome annotation
| Autor: | Pierre Pontarotti, Virginie Lopez Rascol, Philippe Gouret, Etienne Danchin, Anthony Levasseur |
|---|---|
| Přispěvatelé: | Architecture et fonction des Macromolécules Biologiques - UMR 6098 (AFMB), Université de Provence - Aix-Marseille 1-Centre National de la Recherche Scientifique (CNRS), Unité mixte de recherche de biotechnologie des champignons filamenteux, Université de la Méditerranée - Aix-Marseille 2-Institut National de la Recherche Agronomique (INRA)-Université de Provence - Aix-Marseille 1, Evolution, Genome, Environnement (EGEE), Université de Provence - Aix-Marseille 1, Pontarotti, Pierre |
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
concept biologique
Process (engineering) processus biologique Context (language use) annotation génomique Bacterial genome size gène paralogue Vertebrate and Genome Annotation Project Biology DNA sequencing 03 medical and health sciences Genetics gène orthologue Amino Acid Sequence [SDV.BDD]Life Sciences [q-bio]/Development Biology Ecology Evolution Behavior and Systematics Information exchange 030304 developmental biology 0303 health sciences Genome Phylum 030302 biochemistry & molecular biology Biologie du développement Computational Biology Genome project Genomics Development Biology Biological Evolution Gene Expression Regulation Evolutionary biology science informatique arbre phylogénétique Molecular Medicine Animal Science and Zoology séquence de gènes Developmental Biology |
| Zdroj: | Journal of Experimental Zoology Part B: Molecular and Developmental Evolution Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Wiley, 2007, 308B (1), pp.26-36. ⟨10.1002/jez.b.21131⟩ Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 2007, 308B (1), pp.26-36. ⟨10.1002/jez.b.21131⟩ Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution 1 (308B), 26-36. (2007) |
| ISSN: | 1552-5007 1552-5015 |
| DOI: | 10.1002/jez.b.21131⟩ |
| Popis: | International audience; The past decade has seen the completion of numerous whole-genome sequencing projects, began with bacterial genomes and continued with eukaryotic species from different phyla: fungi, plants and animals. Besides, more biological information are produced and are shared thanks to information exchange systems, and more biological concepts, as well as more bioinformatics tools, are available. In this article, we will describe how the evolutionary biology concepts, as well as computer science, are useful for a better understanding of biology in general and genome annotation in particular. The genome annotation process consists of taking the raw DNA produced, for example, by the genome sequencing projects, adding the layers of analysis and interpretation necessary to extract its biological significance and placing it in the context of our understanding of biological processes. Genome annotation is a multistep process falling into two broad categories: structural and functional annotation |
| Databáze: | OpenAIRE |
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