Synthesis and secretion of phospholipase C by oral spirochetes
| Autor: | Mervyn Gornitsky, R. Siboo, E. C. S. Chan, W. Al-Joburi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1989 |
| Předmět: |
Microbiology (medical)
Phosphorylcholine Microbiology Choline chemistry.chemical_compound medicine Humans Secretion Treponema Periodontitis chemistry.chemical_classification biology Phospholipase C Hydrolysis medicine.disease biology.organism_classification stomatognathic diseases Enzyme chemistry Type C Phospholipases Bacteria Research Article |
| Popis: | Four strains of oral treponemes and Treponema phagedenis Reiter synthesize and secrete phospholipase C (PLC), which was detected by the hydrolysis of p-nitrophenylphosphorylcholine. PLC was detected in gingival crevicular fluid from diseased but not from healthy sulci. The initiation and progression of periodontal lesions may begin with the hydrolysis of membrane phospholipids by PLC. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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