96-Well solid-phase extraction: a brief history of its development

Autor:	Susan Cole, James R. Merson, Richard F. Venn, Paul V Macrae
Rok vydání:	2005
Předmět:	Bioanalysis Chromatography Pharmaceutical Preparations Chemistry Clinical Biochemistry Extraction (chemistry) Cell Biology General Medicine Solid phase extraction Biochemistry Productivity Chromatography Liquid Analytical Chemistry
Zdroj:	Journal of Chromatography B. 817:77-80
ISSN:	1570-0232
DOI:	10.1016/j.jchromb.2004.08.029
Popis:	This communication describes the invention and further development of the first 96-well solid-phase extraction system and the original purposes to which it was put. We also describe the adaption of this system for bioanalysis of pharmaceutically active small molecules and the needs underlying it. The system has become a world-wide standard for high-throughput bioanalysis and has been extended by others to include, for example, disk-phase extraction and supported liquid-liquid extraction, as well as 384-well systems. The factors that enabled this leap forward in productivity are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e174c1a9c46482b20497800c180e5b https://doi.org/10.1016/j.jchromb.2004.08.029 Zobrazit plný text záznamu Full Text from ScienceDirect