Association between the Occurrence of Primary Hypothyroidism and the Exposure of the Population Near to Industrial Pollutants in São Paulo State, Brazil
| Autor: | Rudá Alessi, Marco Martins, Maria Angela Zaccarelli-Marino, Thalles Zaccarelli Balderi |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Health Toxicology and Mutagenesis Air pollution lcsh:Medicine 010501 environmental sciences medicine.disease_cause 01 natural sciences chemistry.chemical_compound 0302 clinical medicine Prevalence Child AERMOD education.field_of_study Air Pollutants São Paulo state Incidence industrial pollutants Middle Aged petrochemical complex Female Thyroid function Brazil Adult primary hypothyroidism Adolescent Population 030209 endocrinology & metabolism Risk Assessment Article Odds 03 medical and health sciences Young Adult Hypothyroidism Environmental health Air Pollution medicine Humans Industry Nitrogen dioxide education 0105 earth and related environmental sciences Aged Pollutant lcsh:R Public Health Environmental and Occupational Health Environmental Exposure Models Theoretical chemistry Weather Research and Forecasting Model Environmental science |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 16 Issue 18 International Journal of Environmental Research and Public Health, Vol 16, Iss 18, p 3464 (2019) |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph16183464 |
| Popis: | Background: Environmental agents interfere with thyroid function at multiple levels. This study was to investigate the association between pollutant concentrations and the primary hypothyroidism (PH) occurrence odds in residents living in the Capuava Petrochemical Complex (CPC) influence area. Methods: This area was evaluated with the combination of the AERMOD dispersion model with the Weather Research Forecast (WRF) meteorological model (2016). The concentration of atmospheric pollutants were analyzed in 2017 using meteorological data on the period from 2005 to 2009, correlating this data with the research done in 2003 to 2005. A home-based questionnaire was applied to evaluate 2004 residents, of both sexes, aged from 8 to 72 years, based on their proximity to the industrial areas were select residents with PH. Results: Volatile organic compounds (VOCs), carbon monoxide (CO), and nitrogen dioxide (NO2) concentrations presented the highest correlations between the PH odds and pollutant concentrations. Conclusion: Air pollution associated with the presence of the CPC is an important environmental factor contributing to the development of PH in the nearby population. As the first study showing this association in Brazil, research should be continued to better understand the mechanisms and to find ways to compensate for or remedy to avoid health impacts in future populations. |
| Databáze: | OpenAIRE |
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