Characteristics of Guillain-Barré syndrome in a Lebanese tertiary care center
| Autor: | Elia Malek, Johnny Salameh, Helen Ismail, Lea Saroufim |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Adult Male Pediatrics medicine.medical_specialty Guillain-Barre Syndrome Motor symptoms Tertiary care Tertiary Care Centers 03 medical and health sciences Cranial neuropathies Young Adult 0302 clinical medicine Medicine Humans Lebanon Genetics (clinical) Retrospective Studies Guillain-Barre syndrome business.industry Immunoglobulins Intravenous Retrospective cohort study Polyradiculoneuropathy Middle Aged medicine.disease Respiration Artificial 030104 developmental biology Neurology Pediatrics Perinatology and Child Health Female Neurology (clinical) Presentation (obstetrics) business Hospital stay 030217 neurology & neurosurgery |
| Zdroj: | Neuromuscular disorders : NMD. 31(8) |
| ISSN: | 1873-2364 |
| Popis: | Guillain-Barre Syndrome (GBS) is a group of acute inflammatory disorders that share a clinical presentation of progressive polyradiculo-neuropathy. Data on GBS in the Middle East and Lebanon are scarce; hence, we explored the characteristics of patients presenting with GBS to a tertiary care center in Beirut, Lebanon. This was a single-centered retrospective study over a 12-year period. We reviewed the charts of patients presenting with GBS to the American University of Beirut medical center and examined their presentation, management and outcome. 61 patients were included, with the majority being males. 59% of the patients reported an infection prior to admission. 77% had sensory and motor symptoms and 69% were diagnosed with acute inflammatory demyelinating polyneuropathy (AIDP). 57% of patients had initial symptoms in the lower extremities, 25% experienced cranial neuropathies, and 26% complained of pain. 77% were managed by intravenous immunoglobulin with a median hospital stay of 6.5 days. AIDP was noted to be the most prevalent GBS variant in Lebanon. More than 50% had an unfavorable outcome at discharge, which raises the need for better treatment and management approaches. |
| Databáze: | OpenAIRE |
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