Utility of Self-Administered Questionnaires for Identifying Individuals at Risk of COPD in Japan: The OCEAN (Okinawa COPD casE finding AssessmeNt) Study
Autor: | Bruce E. Miller, Mei Haruya, Takeo Ishii, Kentaro Tamaki, Ruth Tal-Singer, Eishin Sakihara, Oksana Kirichek, Shoko Akiyama, Ryosuke Tawara, Hiroaki Miyata, Norimichi Hirahara, Edgar P Simard, Masayuki Katsumata, Toshihiko Kaise |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Adult
Spirometry medicine.medical_specialty Vital capacity Letter Vital Capacity International Journal of Chronic Obstructive Pulmonary Disease Pulmonary Disease Chronic Obstructive 03 medical and health sciences FEV1/FVC ratio 0302 clinical medicine Japan Quality of life Forced Expiratory Volume Surveys and Questionnaires medicine Humans 030212 general & internal medicine COPD Receiver operating characteristic medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease respiratory tract diseases Test (assessment) 030228 respiratory system Quality of Life Physical therapy Observational study business |
Zdroj: | International Journal of Chronic Obstructive Pulmonary Disease |
ISSN: | 1178-2005 |
Popis: | Kentaro Tamaki,1 Eishin Sakihara,2 Hiroaki Miyata,3 Norimichi Hirahara,3 Oksana Kirichek,4 Ryosuke Tawara,5 Shoko Akiyama,5 Masayuki Katsumata,5 Mei Haruya,6 Takeo Ishii,7 Edgar P Simard,8 Bruce E Miller,8 Ruth Tal-Singer,8 Toshihiko Kaise5 1Department of Breast Surgery, Nahanishi Clinic, Okinawa, Japan; 2Lifestyle Related Disease Medical Center, Naha Medical Association, Okinawa, Japan; 3Health Policy and Management, School of Medicine, Keio University, Tokyo, Japan; 4Value Evidence and Outcomes, GSK, Stockley Park, UK; 5Japan Development, GSK, Tokyo, Japan; 6Government Affairs and Market Access, GSK, Tokyo, Japan; 7Medical Japan, GSK, Tokyo, Japan; 8Value Evidence and Outcomes, GSK, Collegeville, PA, USACorrespondence: Toshihiko KaiseJapan Development, GSK, Tokyo, JapanTel +81-80-5927-9500Email toshihiko.kaise@gsk.comPurpose: A considerable proportion of patients with chronic obstructive pulmonary disease (COPD) remain undiagnosed and untreated even though they may have a burden of respiratory symptoms that impact quality of life. The OCEAN study assessed the ability of screening questionnaires to identify individuals with, or at risk of, COPD by comparing questionnaire outcomes with spirometric measures of lung function.Methods: This observational study included participants ≥ 40 years of age presenting for their annual health examination at a single medical center in Okinawa, Japan. Participants completed COPD screening questionnaires (CAPTURE and COPD-Q), the Chronic Airways Assessment Test (CAAT), and general demographic and health-related questionnaires. The performance characteristics of CAPTURE and COPD-Q were compared with spirometry-based airflow limitation by calculating the area under the receiver operating characteristic (ROC-AUC) curve.Results: A total of 2518 participants were included in the study; 79% of whom were < 60 years of age (mean 52.0 years). A total of 52 (2.1%) participants had airflow limitation defined as forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) < 0.7, and 420 (16.7%) participants were classified as Preserved Ratio Impaired Spirometry (PRISm). Among participants with PRISm, 75 (17.9%) had a CAAT total score ≥ 10. Airflow limitation and PRISm were more prevalent in current smokers versus past smokers. For the CAPTURE questionnaire, ROC-AUC for screening airflow limitation, PRISm, and PRISm with a CAAT total score ≥ 10 were 0.59, 0.55, and 0.69, respectively; for COPD-Q, these three clinical features were 0.67, 0.58 and 0.68, respectively.Conclusion: This study demonstrated that CAPTURE and COPD-Q appear to be effective screening tools for identifying symptomatic individuals with undiagnosed, or at risk of developing COPD in adults ≥ 40 years of age in Okinawa. Furthermore, early diagnosis and management of PRISm is important to improve future outcomes and the societal burden of disease.Keywords: COPD, CAAT, COPD-Q, Japan, PRISm, CAPTURE |
Databáze: | OpenAIRE |
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