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Objective; The determine the frequency of Allergic Broncho Pulmonary Aspergillosis in cases of bronchial asthma. Methodology: This was a cross sectional study carried out at Department of Medicine, Services Hospital, Lahore during 01-07-2017 to 31-12-2017. In this study, the cases of both genders and age range of 18 to 60 years having known history of bronchial asthma were included. The diagnosis of bronchial asthma was made by clinical history and on Pulmonary function tests with FEV1/FVC ratio of less than 0.7 and post broncho dilatation the change in FEV1 of > 12%. ABPA was labelled as yes where there was serum IgE level more than 1000 IU/ml and central bronchiectasis of HRCT chest. Results: In this study, the 100 cases of bronchial asthma were included. The mean age was 31.24±8.78 years (table 1) and out of these 100 cases, 67 (67%) were males and 33 (33%) were females. ABPA was observed in 18 (18%) of the cases. ABPA was seen seen in 16 (24.24%) cases with severe disease as compared to 02 (5.88%) cases with moderate degree of disease with of significant p value of 0.001 (table 2). There was also near significant difference where ABPA was seen in 12 (20%) of the cases with duration more than 3 years with p= 0.09. Conclusion; ABPA is an under rated complication of bronchial asthma and it is significantly high in cases having severe degree of disease. Key Words: Bronchial asthma, ABPA. |
