A micronutrient-fortified young-child formula improves the iron and vitamin D status of healthy young European children: a randomized, double-blind controlled trial
| Autor: | Johannes B. van Goudoever, Simone R.B.M. Eussen, Judith M. van der Horst-Graat, Marjolijn D. Akkermans, Frank Brus, Ruurd M. van Elburg |
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| Přispěvatelé: | ARD - Amsterdam Reproduction and Development, Neonatology, General Paediatrics, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male Pediatrics Cow milk Young children Medicine (miscellaneous) Gastroenterology law.invention Hemoglobins Randomized controlled trial law Youngchild formula Micronutrients Vitamin D Micronutrient fortification Nutrition and Dietetics Anemia Iron-Deficiency Iron deficiency Iron Deficiencies Micronutrient Infant Formula Europe C-Reactive Protein Milk Health & Consumer Research Child Preschool Food Fortified Female Vitamin D supplements medicine.medical_specialty Iron Fortification Nutritional Status vitamin D deficiency White People Double blind 03 medical and health sciences Double-Blind Method Internal medicine medicine Vitamin D and neurology Animals Humans Food Health & Consumer Research 030109 nutrition & dietetics Vitamin D deficiency business.industry Infant medicine.disease Food Ferritins business |
| Zdroj: | American journal of clinical nutrition, 105(2), 391-399. American Society for Nutrition American Journal of Clinical Nutrition, 105(2), 391-399 American Journal of Clinical Nutrition 105 (2017) 2 |
| ISSN: | 0002-9165 |
| Popis: | Background: Iron deficiency (ID) and vitamin D deficiency (VDD) are common among young European children because of low dietary intakes and low compliance to vitamin D supplementation policies. Milk is a common drink for young European children. Studies evaluating the effect of milk fortification on iron and vitamin D status in these children are scarce. Objective: We aimed to investigate the effect of a micronutrient-fortified young-child formula (YCF) on the iron and vitamin D status of young European children. Design: In this randomized, double-blind controlled trial, healthy German, Dutch, and English children aged 1–3 y were allocated to receive either YCF (1.2 mg Fe/100 mL; 1.7 μg vitamin D/100 mL) or nonfortified cow milk (CM) (0.02 mg Fe/100 mL; no vitamin D) for 20 wk. Blood samples were taken before and after the intervention. The primary and secondary outcomes were change from baseline in serum ferritin (SF) and 25-hydroxyvitamin D [25(OH)D], respectively. ID was defined as SF |
| Databáze: | OpenAIRE |
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