Gold-Catalyzed Tandem Oxidative Coupling Reaction between β-Ketoallenes and Electron-Rich Arenes to 2-Furylmethylarenes

Autor:	Hironao Sajiki, Yuya Miki, Chikara Furugen, Yoshinari Sawama, Naoki Yasukawa, Yutaro Yamada
Rok vydání:	2021
Předmět:	chemistry.chemical_classification Tandem Allene Organic Chemistry Salt (chemistry) Biochemistry Catalysis chemistry.chemical_compound chemistry Nucleophile Polymer chemistry Moiety Surface modification Oxidative coupling of methane Physical and Theoretical Chemistry
Zdroj:	Organic Letters. 23:5891-5895
ISSN:	1523-7052 1523-7060
Popis:	A tandem oxidative coupling reaction of β-ketoallenes and arenes was developed, which leads to the formation of 2-furylmethylarenes using AuCl3 and phenyliodine diacetate. The AuIII salt catalyzed the cyclization of β-ketoallenes to form a 2-furylmethyl gold intermediate, and the subsequent C-H functionalization of arenes proceeded smoothly. During the oxidative coupling, nucleophilic additions occurred at the center and terminal carbon atoms of the allene moiety to form C-O and C-C bonds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cc922718d78b64f2dce613c73d0b34 https://doi.org/10.1021/acs.orglett.1c02007 Zobrazit plný text záznamu