Immunotropic influence of 900 MHz microwave GSM signal on human blood immune cells activated in vitro
| Autor: | Marek Dabrowski, Roman Kubacki, Elzbieta Sobiczewska, Stanislaw Szmigielski, Wanda Stankiewicz |
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| Rok vydání: | 2006 |
| Předmět: |
Chemistry
Lymphocyte Cell Cycle Biophysics Medicine (miscellaneous) Dose-Response Relationship Radiation General Medicine Cell cycle Peripheral blood mononuclear cell Molecular biology In vitro Monocytes Monokine Dose–response relationship Immune system medicine.anatomical_structure Electromagnetic Fields Immunology medicine Humans Lymphocytes Microwaves Microwave Cells Cultured |
| Zdroj: | Electromagnetic biology and medicine. 25(1) |
| ISSN: | 1536-8378 |
| Popis: | In an earlier study we reported that G(o) phase peripheral blood mononulclear cells (PBMC) exposed to low-level (SAR = 0.18 W/kg) pulse-modulated 1300 MHz microwaves and subsequently cultured, demonstrate changed immune activity (Dabrowski et al., 2003). We investigated whether cultured immune cells induced into the active phases of cell cycle (G(1), S) and then exposed to microwaves will also be sensitive to electromagnetic field. An anechoic chamber of our design containing a microplate with cultured cells and an antenna emitting microwaves (900 MHz simulated GSM signal, 27 V/m, SAR 0.024 W/kg) was placed inside the ASSAB incubator. The microcultures of PBMC exposed to microwaves demonstrated significantly higher response to mitogens and higher immunogenic activity of monocytes (LM index) than control cultures. LM index, described in detail elsewhere (Dabrowski et al., 2001), represents the monokine influence on lymphocyte mitogenic response. The results suggest that immune activity of responding lymphocytes and monocytes can be additionally intensified by 900 MHz microwaves. |
| Databáze: | OpenAIRE |
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