Cortisol Levels and Gastrointestinal Disorders After Stressful Surgery in Rabbits
| Autor: | Soo Jin Son, Seok Hwa Choi, Seong Soo Kang, Jaeyeon Lee, Seok Jin Jang, Gonhyung Kim |
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| Rok vydání: | 2017 |
| Předmět: |
Cancer Research
medicine.medical_specialty Hydrocortisone Gastrointestinal Diseases 040301 veterinary sciences Tracheal surgery Postoperative pain Appetite Anorexia General Biochemistry Genetics and Molecular Biology 0403 veterinary science 03 medical and health sciences Postoperative Complications 0302 clinical medicine medicine Animals Humans Water intake Cortisol level Pharmacology Analgesics Pain Postoperative business.industry 030206 dentistry 04 agricultural and veterinary sciences Surgery Disease Models Animal Diarrhea Poor Appetite Gastrointestinal disorder Anesthesia Rabbits medicine.symptom business Stress Psychological Research Article |
| Zdroj: | In Vivo. 31:637-640 |
| ISSN: | 1791-7549 |
| Popis: | Rabbits are widely used in biomedical studies because they are docile and manageable. However, they are prone to gastrointestinal disorders due to their vulnerability to stress. Eighteen adult rabbits were used for allogenic tracheal surgery. The tracheas for allograft, 20-mm length, were transplanted into 20-mm tracheal defects. Immediately after surgery, most rabbits suffered from poor appetite. Food and water intake gradually recovered within 7 days after surgery, but six rabbits had severe anorexia from day 7 post-surgery. Four of these rabbits developed symptoms of diarrhea after surgery; three of them died several days after the onset of diarrhea, while one rabbit recovered. Gastrointestinal disorders need to be prevented in rabbits undergoing stressful surgery. Furthermore, it is important to choose the proper type and dose of analgesics in order to relieve postoperative pain. With this observation in mind, rabbits are not considered to be an appropriate model for stressful surgery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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