Study of the efficacy of pipelle biopsy technique to diagnose endometrial diseases in abnormal uterine bleeding
| Autor: | Nanda Kishore Alva, C Raja Ilavarasi, G S Jyothi |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Health (social science) medicine.medical_treatment Abnormal uterine bleeding Medicine (miscellaneous) endometrial carcinoma lcsh:Geriatrics lcsh:Gynecology and obstetrics 03 medical and health sciences 0302 clinical medicine Positive predicative value Biopsy medicine Carcinoma Outpatient clinic pipelle biopsy 030212 general & internal medicine hysterectomy Prospective cohort study lcsh:RG1-991 030219 obstetrics & reproductive medicine Hysterectomy medicine.diagnostic_test business.industry medicine.disease Curettage Endometrial hyperplasia lcsh:RC952-954.6 Original Article Radiology business endometrial hyperplasia |
| Zdroj: | Journal of Mid-Life Health Journal of Mid-Life Health, Vol 10, Iss 2, Pp 75-80 (2019) |
| ISSN: | 0976-7800 |
| DOI: | 10.4103/jmh.jmh_109_18 |
| Popis: | Background: Pipelle biopsy is ideal for obtaining endometrial sample in outpatient department. It samples only 4% of the endometrial surface and has sensitivity up to 97%. A positive biopsy can avoid inconvenience to a patient, but a nonspecific finding should be interpreted with caution. Thus, the objectives of this study were to analyze the efficacy of pipelle biopsy by adequacy of the sample obtained and also to establish the reliability by comparing the histopathology report obtained by pipelle biopsy with that of the hysterectomy specimen. Materials and Methods: A prospective study conducted at a tertiary care hospital on 104 women with abnormal uterine bleeding (AUB). They were scheduled for pipelle endometrial sampling before hysterectomy. The sensitivity, specificity, negative and positive predictive values, and accuracy of pipelle biopsy in diagnosing various endometrial pathologies were analyzed. The validity of pipelle biopsy was studied for endometrial hyperplasia and carcinoma and their statistical significance was tested. Results: The overall concordance rate was 63.8%. The sensitivity, specificity, positive and negative predictive values, and accuracy of pipelle biopsy for endometrial hyperplasia was 64.2%, 88.8%, 94.1%, 85.5%, and 47.3% and for endometrial carcinoma was 75%, 100%, 100%, 97.9%, and 98%, respectively. The P value for endometrial hyperplasia and carcinoma was 0.001 (statistically significant). Conclusion: Pipelle biopsy is valuable in diagnosing endometrial pathology of AUB cases. It has very high sensitivity and specificity for endometrial malignancies. A hysteroscopic dilatation and curettage is required for definitive diagnosis in cases of polyps and focal endometrial lesions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |