Editorial: Gateway to monocyte entry into the brain: CXCR7, the new orchestra conductor

Autor: Steven D. Douglas, Sergei Spitsin
Rok vydání: 2017
Předmět:
CD4-Positive T-Lymphocytes
Male
0301 basic medicine
Lipopolysaccharide Receptors
Human immunodeficiency virus (HIV)
Gene Expression
HIV Infections
medicine.disease_cause
Monocytes
Antiretroviral Therapy
Highly Active

Immunology and Allergy
virus diseases
Brain
hemic and immune systems
Middle Aged
Viral Load
medicine.anatomical_structure
Blood-Brain Barrier
embryonic structures
Female
biological phenomena
cell phenomena
and immunity

Signal transduction
Signal Transduction
Adult
Receptors
CXCR4

Primary Cell Culture
Immunology
Biology
GPI-Linked Proteins
Blood–brain barrier
Models
Biological

03 medical and health sciences
Cell Line
Tumor

medicine
Humans
Immunologic Factors
Cognitive Dysfunction
Receptors
CXCR

Monocyte
Receptors
IgG

Editorials
Transendothelial and Transepithelial Migration
Endothelial Cells
Chemotaxis
Cell Biology
Gateway (computer program)
biological factors
Chemokine CXCL12
CD4 Lymphocyte Count
030104 developmental biology
Astrocytes
HIV-1
Spotlight on Leading Edge Research
Neuroscience
Zdroj: Journal of Leukocyte Biology. 102:1155-1157
ISSN: 1938-3673
0741-5400
DOI: 10.1189/jlb.3ce0717-273r
Popis: Discussion on the potential role for CXCR7 as a major signaling pathway for CD14+CD16+ monocyte transmigration across the blood brain barrier, and its therapeutic application for NeuroAIDS.
Databáze: OpenAIRE