Timing of renal replacement therapy and long-term risk of chronic kidney disease and death in intensive care patients with acute kidney injury
| Autor: | J. Bradley Layton, Lars Pedersen, Steffen Christensen, Christian Fynbo Christiansen, Søren Christiansen, Henrik Gammelager, M. Alan Brookhart |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Denmark Population Critical Care and Intensive Care Medicine urologic and male genital diseases law.invention End stage renal disease Cohort Studies 03 medical and health sciences End-stage renal disease 0302 clinical medicine law Risk Factors Internal medicine Intensive care Chronic kidney disease Journal Article Medicine Humans 030212 general & internal medicine Renal replacement therapy Timing Hospital Mortality Renal Insufficiency Chronic education Aged education.field_of_study business.industry Research lcsh:Medical emergencies. Critical care. Intensive care. First aid Acute kidney injury 030208 emergency & critical care medicine lcsh:RC86-88.9 Acute Kidney Injury Middle Aged medicine.disease Intensive care unit female genital diseases and pregnancy complications Intensive Care Units Female business Cohort study Kidney disease |
| Zdroj: | Critical Care Christiansen, S, Christensen, S, Pedersen, L, Gammelager, H, Layton, J B, Brookhart, M A & Christiansen, C F 2017, ' Timing of renal replacement therapy and long-term risk of chronic kidney disease and death in intensive care patients with acute kidney injury ', Critical Care (Online Edition), vol. 21, no. 1, pp. 326 . https://doi.org/10.1186/s13054-017-1903-y Critical Care, Vol 21, Iss 1, Pp 1-9 (2017) |
| ISSN: | 1466-609X 1364-8535 |
| Popis: | Background The optimal time to initiate renal replacement therapy (RRT) in intensive care unit (ICU) patients with acute kidney injury (AKI) is unclear. We examined the impact of early RRT on long-term mortality, risk of chronic kidney disease (CKD), and end-stage renal disease (ESRD). Methods This cohort study included all adult patients treated with continuous RRT in the ICU at Aarhus University Hospital, Skejby, Denmark (2005–2015). Data were obtained from a clinical information system and population-based registries. Early treatment was defined as RRT initiation at AKI stage 2 or below, and late treatment was defined as RRT initiation at AKI stage 3. Inverse probability of treatment (IPT) weights were computed from propensity scores. The IPT-weighted cumulative risk of CKD (estimated glomerular filtration rate |
| Databáze: | OpenAIRE |
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