Hepatitis C Virus Infection as a Traumatic Experience
| Autor: | Lucas C. Quarantini, Maria Isabel Schinoni, K.M. Pettersen, Adriana Dantas-Duarte, Carlos Antonio de Souza Teles Santos, Lucas Araújo-de-Freitas, Luciana Di-Domizio Amaral, Raymundo Paraná, Patrícia Cavalcanti-Ribeiro, Liana R. Netto, Mychelle Morais-de-Jesus, Ângela Miranda-Scippa, Renato Daltro-Oliveira, Karestan C. Koenen |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Post-traumatic stress disorder--Diagnosis Epidemiology Gastroenterology and hepatology lcsh:Medicine Disease Hepacivirus medicine.disease_cause Stress Disorders Post-Traumatic Quality of life Young adult lcsh:Science Multidisciplinary Hepatitis C virus Hepatitis C Middle Aged Anxiety Disorders Infectious hepatitis Mental health Female Brazil Research Article Adult medicine.medical_specialty Neuropsychiatric Disorders Medical sciences Young Adult Internal medicine Mental Health and Psychiatry medicine Humans Psychiatry Liver diseases Aged Demography Medicine and health sciences business.industry lcsh:R Hepatitis C Chronic medicine.disease Multivariate Analysis Quality of Life lcsh:Q business Stress Psychological Biomedical sciences |
| Zdroj: | PLoS ONE PLoS ONE, Vol 9, Iss 10, p e110529 (2014) |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0110529 |
| Popis: | Objective The purpose of this study was to evaluate whether individuals consider their HCV infection to be a potentially traumatic experience. Additionally, we investigated its association with Post-Traumatic Stress Disorder (PTSD) and the impact of PTSD diagnosis on health-related quality of life (HRQoL) in HCV infected subjects. Methods We conducted a cross-sectional survey of 127 HCV-infected outpatients recruited at a University Hospital in Salvador, Brazil. All subjects answered an orally-administered questionnaire to gather clinical and socio-demographic data. We investigated traumatic experiences and the subject's perception of the disease using the Trauma History Questionnaire. PTSD and other psychiatric diagnoses were assessed through the Mini International Neuropsychiatric Interview-Brazilian Version 5.0.0 (M.I.N.I. PLUS). HRQoL was assessed using Short-Form 36 (SF-36). Results Approximately 38.6% of the patients considered hepatitis C to be a traumatic experience. Of these, 60.7% had a PTSD diagnosis. PTSD was associated with significant impairment in quality of life for individuals in seven SF-36 domains as shown bymultivariate analysis: Role-Physical (β: −24.85; 95% CI: −42.08; −7.61), Bodily Pain (β: −19.36; 95% CI: −31.28; −7.45), General Health (β: −20.79; 95% CI: −29.65; −11.92), Vitality (β: −11.92; 95% CI: −20.74; −3.1), Social Functioning (β: −34.73; 95% CI: −46.79; −22.68), Role-Emotional (β: −26.07; 95% CI: −44.61; −7.53), Mental Health (β: −17.46; 95% CI: −24.38; −10.54). Conclusion HCV is frequently a traumatic experience and it is strongly associated with PTSD diagnosis. PTSD significantly impaired HRQoL. |
| Databáze: | OpenAIRE |
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