Functional Outcomes Following Microfragmented Adipose Tissue Versus Bone Marrow Aspirate Concentrate Injections for Symptomatic Knee Osteoarthritis
Autor: | Kirk Easley, Ryan Robinson, Zachary Fausel, Robert Bowers, Kenneth Mautner |
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Rok vydání: | 2019 |
Předmět: |
Male
0301 basic medicine medicine.medical_specialty Visual analogue scale Adipose Arthritis Adipose tissue Bone Marrow Cells Stem cells Osteoarthritis Injections Intra-Articular 03 medical and health sciences 0302 clinical medicine Bone marrow aspirate Human Clinical Article Quality of life medicine Humans Bone marrow Prospective Studies lcsh:QH573-671 Bone Marrow Transplantation Retrospective Studies Adult stem cells lcsh:R5-920 lcsh:Cytology business.industry Significant difference Cell Biology General Medicine Middle Aged Osteoarthritis Knee Prognosis medicine.disease Adipose stem cells Surgery 030104 developmental biology medicine.anatomical_structure Adipose Tissue Quality of Life Mesenchymal stem cells Female lcsh:Medicine (General) business 030217 neurology & neurosurgery Developmental Biology |
Zdroj: | Stem Cells Translational Medicine, Vol 8, Iss 11, Pp 1149-1156 (2019) Stem Cells Translational Medicine |
ISSN: | 2157-6580 2157-6564 |
Popis: | This study aimed to determine whether autologous orthobiologic tissue source affects pain and functional outcomes in patients with symptomatic knee osteoarthritis (OA) who received microfragmented adipose tissue (MFAT) or bone marrow aspirate concentrate (BMAC) injection. We retrospectively reviewed prospectively collected data from patients who received BMAC or MFAT injection for symptomatic knee OA. Patients completed baseline and follow-up surveys. Each survey included the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire, Emory Quality of Life (EQOL) questionnaire, and Visual Analog Scale (VAS) for pain. The follow-up responses were compared with baseline for all patients and between BMAC and MFAT groups. A total of 110 patients met inclusion criteria, with 76 patients (BMAC 41, MFAT 35) and 106 knees (BMAC 58, MFAT 48) having appropriate follow-up data. The BMAC group included 17 females and 24 males, with a mean age of 59 ± 11 years. The MFAT group included 23 females and 12 males, with a mean age of 63 ± 11 years. Minimum follow-up time was 0.5 years. Mean follow-up time was 1.80 ± 0.88 years for BMAC and 1.09 ± 0.49 years for MFAT. Both groups had significant improvement in EQOL, VAS, and all KOOS parameters preprocedure versus postprocedure (p |
Databáze: | OpenAIRE |
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