Risk of depression following traumatic limb amputation : a general population-based cohort study
| Autor: | Ayako Hiyoshi, Helen Y N Lindner, Scott Montgomery |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male 030506 rehabilitation medicine.medical_specialty medicine.medical_treatment Poison control Orthopaedics Suicide prevention Occupational safety and health Cohort Studies 03 medical and health sciences 0302 clinical medicine traumatic Amputation Traumatic Risk Factors Injury prevention Health Sciences Medicine Humans Gerontologi medicinsk/hälsovetenskaplig inriktning Gerontology specialising in Medical and Health Sciences Amputation Depression (differential diagnoses) Sweden Prosthetics business.industry Public Health Environmental and Occupational Health Human factors and ergonomics General Medicine cohort Middle Aged Hälsovetenskaper Cohort depression Ortopedi Physical therapy 0305 other medical science business 030217 neurology & neurosurgery |
| Zdroj: | Publikationer från Örebro universitet. |
| Popis: | Background: Individuals with traumatic limb amputation (TLA) may be at risk of depression, but evidence of increased depression after TLA from longitudinal studies has been limited. It is also unknown whether physical function, cognitive function, and employment prior to amputation affects depression risk. We aimed to examine longitudinal associations between TLA and depression in working age men, and to explore the role of pre-amputation occupational and individual characteristics. Methods: A Swedish national register-based cohort of 189,220 men born between 1952 and 1956, and who attended conscription assessments in adolescence, was followed from 1985 to 2009. Physical, cognitive, and psychological characteristics were measured at the conscription examination, and occupational information was obtained from the 1985 census. Main outcome measures were hospital inpatient and outpatient admissions for depression. Results: In total, 401 men underwent TLA; mean age at amputation was 42.5 years (SD 7.4). Cox regression produced an unadjusted hazard ratio (95% confidence interval) of 2.61 (1.62–4.21) for risk of subsequent depression associated with TLA compared with the general population. Adjustment for occupational, physical, cognitive, and psychological characteristics did not change the association much, producing a hazard ratio of 2.53 (1.57–4.08). Conclusions: TLA is associated with an increased risk of depression in men over more than two decades of follow up. Occupational and individual characteristics prior to amputation did not greatly change depression risk following amputation. We speculate that a coordinated combination of social support and medical management may help reduce persistent depression risk in men who experience amputation. Funding Agencies:Örebro University Hospital Research Foundation OLL-488821 429431 UK Economic and Social Research Council (ESRC) RES-596-28-0001 ES/JO19119/1 |
| Databáze: | OpenAIRE |
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