Effect of flunixin meglumine or prostaglandin E2 treatment 15 days after breeding on fertility in Saanen does
| Autor: | Sait Sendag, Axel Wehrend, Mesih Kocamüftüoğlu, İbrahim Küçükaslan, Yunus Çetin, Nihat Özyurtlu |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Pregnancy Rate Prostaglandin Antagonists media_common.quotation_subject Fertility Breeding Luteal Phase Luteal phase Dinoprostone Animal science Food Animals Corpus Luteum Pregnancy Internal medicine Animals Medicine Prostaglandin E2 Small Animals media_common Estrous cycle Equine business.industry Goats Fecundity medicine.disease Clonixin Pregnancy rate medicine.anatomical_structure Endocrinology Female Animal Science and Zoology business Corpus luteum medicine.drug |
| Zdroj: | Theriogenology. 81:424-427 |
| ISSN: | 0093-691X |
| DOI: | 10.1016/j.theriogenology.2013.10.015 |
| Popis: | The objective of this study was to determine the effects of timely injections of flunixin meglumine (FM) or vaginal application of prostaglandin E2 (PgE(2)) on pregnancy, fertility, fecundity, and prolificacy rates in Saanen goats. One hundred and sixty-three nonlactating Saanen does were treated with a flugestone acetate (20 mg)-containing intravaginal sponge for 12 days. They also received eCG (400 IU) and a PGF(2 alpha) analogue (50 mu g) 10 days after progestagen priming. Does detected in estrus were mated and assigned randomly to one of three treatment groups. The PgE(2) group (N = 40) received PgE(2) (2.5 mg) intravaginally 15 days after mating. The FM group (N = 54) received flunixin meglumine (total dose, 100 mg) intramuscularly 15 days after mating. Flunixin meglumine was administered at 9:00 AM. Animals in the control group (N = 69) received no treatment. Pregnancy was diagnosed using transrectal ultrasonography (B-mode at 8 MHz) 30 days after mating. The pregnancy rate was significantly greater (P < 0.01) after 30 days in goats treated with PgE(2) and also in the control group than in those treated with FM (67.5%, 59.4%, and 42.5%, respectively). The pregnancy rate did not differ between the PgE(2) and the control group. The pregnancy and fertility rate were lowest in the FM group compared with the other groups. There was no significant difference in the prolificacy rate among experimental groups. In conclusion, our results showed that FM administration during a late luteal phase is detrimental to early pregnancy in goats. (C) 2014 Elsevier Inc. All rights reserved. |
| Databáze: | OpenAIRE |
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