Safety of coloanal/ileoanal anastomosis during cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: results of 20 consecutive patients
| Autor: | Murat Kalin, Ozgul Duzgun |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male safety Medicine (General) medicine.medical_specialty Clinical Research Reports Colorectal cancer colorectal cancer Biochemistry hyperthermic intraperitoneal chemotherapy 03 medical and health sciences R5-920 0302 clinical medicine medicine Humans Cytoreductive surgery Peritoneal Neoplasms Aged business.industry Anastomosis Surgical coloanal/ileoanal anastomosis Biochemistry (medical) peritoneal carcinomatosis Cytoreduction Surgical Procedures Hyperthermia Induced Cell Biology General Medicine Middle Aged medicine.disease Ileoanal anastomosis Surgery Peritoneal carcinomatosis 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology Hyperthermic intraperitoneal chemotherapy Neoplasm Recurrence Local business |
| Zdroj: | Journal of International Medical Research, Vol 47 (2019) The Journal of International Medical Research |
| ISSN: | 1473-2300 0300-0605 |
| Popis: | Objective No studies to date have focused on the safety of coloanal/ileoanal anastomosis (CAIAA) in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS + HIPEC), which is associated with severe morbidity and mortality. We herein present the outcomes of patients with peritoneal carcinomatosis (PC) who underwent CAIAA. Methods We evaluated the prospectively collected data from 20 patients with PC who underwent CRS + HIPEC with respect to the primary disease, synchronous resections, intraoperative chemotherapy regimen, timing of protective ileostomy closure, and overall postoperative complications. Results Most patients underwent CRS + HIPEC and CAIAA for PC due to colorectal cancer. Coloanal anastomosis was performed in 15 (75%) patients, and J-pouch ileoanal anastomosis was performed in 5 (25%) patients. No anastomosis-related complications occurred in any patients who underwent CAIAA; however, one patient died of pulmonary embolism on postoperative day 7. Conclusions CAIAA is associated with serious complications even after performing benign colorectal surgery. However, it may be challenging for surgeons to simultaneously perform CAIAA in patients with PC who undergo CRS + HIPEC. We emphasize that this procedure can be safely performed with experienced surgical teams by using a multidisciplinary approach. |
| Databáze: | OpenAIRE |
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