Six-month survival and quality of life of intensive care patients with acute kidney injury

Autor: Outi Inkinen, Simo-Pekka Koivisto, Matti Reinikainen, Anna-Maija Korhonen, Suvi T. Vaara, Sara Nisula, Ville Pettilä, Meri Poukkanen, Pekka Tiainen, Kirsi-Maija Kaukonen
Rok vydání: 2013
Předmět:
Male
medicine.medical_specialty
Critical Care
medicine.medical_treatment
030232 urology & nephrology
urologic and male genital diseases
Critical Care and Intensive Care Medicine
03 medical and health sciences
0302 clinical medicine
Quality of life
Intensive care
Surveys and Questionnaires
medicine
Humans
Renal replacement therapy
Prospective Studies
Intensive care medicine
Prospective cohort study
Survival rate
Finland
Aged
urogenital system
business.industry
Incidence (epidemiology)
Research
Incidence
Acute kidney injury
030208 emergency & critical care medicine
Acute Kidney Injury
Length of Stay
Middle Aged
ta3121
medicine.disease
humanities
female genital diseases and pregnancy complications
3. Good health
Survival Rate
Treatment Outcome
Cohort
Quality of Life
Female
business
Biomarkers
Follow-Up Studies
Zdroj: Critical Care
ISSN: 1364-8535
Popis: Introduction Acute kidney injury (AKI) has high incidence among the critically ill and associates with dismal outcome. Not only the long-term survival, but also the quality of life (QOL) of patients with AKI is relevant due to substantial burden of care regarding these patients. We aimed to study the long-term outcome and QOL of patients with AKI treated in intensive care units. Methods We conducted a predefined six-month follow-up of adult intensive care unit (ICU) patients from the prospective, observational, multi-centre FINNAKI study. We evaluated the QOL of survivors with the EuroQol (EQ-5D) questionnaire. We included all participating sites with at least 70% rate of QOL measurements in the analysis. Results Of the 1,568 study patients, 635 (40.5%, 95% confidence interval (CI) 38.0-43.0%) had AKI according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria. Of the 635 AKI patients, 224 (35.3%), as compared to 154/933 (16.5%) patients without AKI, died within six months. Of the 1,190 survivors, 959 (80.6%) answered the EQ-5D questionnaire at six months. The QOL (median with Interquartile range, IQR) measured with the EQ-5D index and compared to age- and sex-matched general population was: 0.676 (0.520-1.00) versus 0.826 (0.812-0.859) for AKI patients, and 0.690 (0.533-1.00) versus 0.845 (0.812-0.882) for patients without AKI (P
Databáze: OpenAIRE
Externí odkaz: