Epithelial Patterning, Morphogenesis, and Evolution: Drosophila Eggshell as a Model
| Autor: | Celeste A. Berg, Stanislav Y. Shvartsman, Miriam Osterfield |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Cell type Morphogenesis Cell Biology Biology biology.organism_classification Biological Evolution Models Biological Epithelium Article General Biochemistry Genetics and Molecular Biology Cell biology Egg Shell 03 medical and health sciences Drosophila melanogaster 030104 developmental biology Bmp signaling Animals Eggshell Molecular Biology Drosophila Body Patterning Developmental Biology |
| Zdroj: | Developmental Cell. 41:337-348 |
| ISSN: | 1534-5807 |
| DOI: | 10.1016/j.devcel.2017.02.018 |
| Popis: | Understanding the mechanisms driving tissue and organ formation requires knowledge across scales. How do signaling pathways specify distinct tissue types? How does the patterning system control morphogenesis? How do these processes evolve? The Drosophila egg chamber, where EGF and BMP signaling intersect to specify unique cell types that construct epithelial tubes for specialized eggshell structures, has provided a tractable system to ask these questions. Work there has elucidated connections between scales of development, including across evolutionary scales, and fostered the development of quantitative modeling tools. These tools and general principles can be applied to the understanding of other developmental processes across organisms. |
| Databáze: | OpenAIRE |
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