Ocular manifestations of coronavirus disease 2019
| Autor: | Bostanci Ceran, Basak, Ozates, Serdar |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Turkey Photophobia Cross-sectional study Lymphocyte Eye Infections Viral Eye Gastroenterology 0302 clinical medicine Basic Science 030212 general & internal medicine Young adult Respiratory system Child Letter to the Editor Aged 80 and over Lacrimal Apparatus Diseases Episcleritis Middle Aged Sensory Systems medicine.anatomical_structure Female medicine.symptom Coronavirus Infections Adult Chemosis medicine.medical_specialty Adolescent Pneumonia Viral Hyperemia Real-Time Polymerase Chain Reaction Betacoronavirus Conjunctivitis Viral Young Adult 03 medical and health sciences Cellular and Molecular Neuroscience Internal medicine medicine Humans Lymphocyte Count Neutrophil to lymphocyte ratio Pandemics Aged SARS-CoV-2 business.industry COVID-19 Conjunctivitis medicine.disease Acute phase reactants Ophthalmology Cross-Sectional Studies 030221 ophthalmology & optometry business Scleritis |
| Zdroj: | Graefes Archive for Clinical and Experimental Ophthalmology Graefe's Archive for Clinical and Experimental Ophthalmology |
| ISSN: | 1435-702X 0721-832X |
| DOI: | 10.1007/s00417-020-04777-7 |
| Popis: | Purpose Coronavirus disease 2019 (COVID-19) is an ongoing global public health problem, and most of the COVID-19 research is focused mainly on the respiratory system because of life-threatening results. However, manifestations in other organs should not be ignored since they can also be a mode of transmission. We sought to describe the ocular manifestations of COVID-19 and investigate the association between ocular involvement and clinical presentation and laboratory outcomes. Methods This cross-sectional study was conducted between March 1, 2020, and April 30, 2020. Ninety-three sequentially hospitalized and clinically confirmed COVID-19 patients were included in the study. The systemic and ocular symptoms, clinical findings, and laboratory outcomes were recorded. Results Of the 93 COVID-19 patients, 54 (58.1%) were male, and 39 (41.9%) were female. Mean age of the patients was 39.4 ± 21.9 (min 7, max 88) years. Twenty patients (n 21.5%) had at least one ocular abnormality. Most common findings included hyperemia (n = 20), epiphora (n = 9), increased secretion (n = 6), chemosis (n = 3), follicular conjunctivitis (n = 2), and episcleritis (n = 2). The most common symptom was photophobia (n 15). Patients with ocular involvement were more likely to have higher neutrophil counts (p = 0.001), and increased CRP (p < 0.001), PCT (p = 0.001), and ESR levels (p < 0.001). Mean lymphocyte count was statistically lower in patients with ocular manifestations (p = 0.001). Mean age and number of patients with fever over 37.3 °C in the ocular involvement group was found to be higher (p < 0.001, p = 0.006, respectively). Conclusion Older age, high fever, increased neutrophil/lymphocyte ratio, and high levels of acute phase reactants seemed to be risk factors for ocular involvement. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink