[Watch out for a second train]
| Autor: | Adélaïde Toutée, Myrto Costopoulos, Clotilde Bravetti, Frederic Davi, Elise Chapiro, Michaël Degaud, Agathe Maillon, Sylvain Choquet, Magali Le Garff-Tavernier, Anne Lavaud, Anne de Septenville, Karim Maloum, Frédéric Charlotte |
|---|---|
| Jazyk: | francouzština |
| Rok vydání: | 2020 |
| Předmět: |
Male
Pathology medicine.medical_specialty Vision Low Monoclonal Gammopathy of Undetermined Significance Flow cytometry Immunophenotyping Diagnosis Differential Nasal fossae Medicine Humans B cell Aged Carcinoma Transitional Cell Incidental Findings Hematologic Tests medicine.diagnostic_test business.industry Eye Neoplasms Waldenstrom macroglobulinemia General Medicine medicine.disease medicine.anatomical_structure Immunoglobulin M Urinary Bladder Neoplasms Lymphoma Large B-Cell Diffuse Urothelium Waldenstrom Macroglobulinemia business Diffuse large B-cell lymphoma |
| Zdroj: | Annales de biologie clinique. 78(5) |
| ISSN: | 1950-6112 |
| Popis: | We report the case of a man with a primary diagnosis of Waldenstrom macroglobulinemia. He secondarily presented a diffuse large B cell lymphoma (DLBCL) located in the nasal fossae, which relapsed later in the eye. The diagnosis of these two malignancies is based on a multidisciplinary biological approach using new sensitive and specific techniques. These techniques revealed that the two diseases harbor different B cell clones, indicating a distinct origin. This observation highlights the importance of targeted biological techniques for the diagnosis of these two rare hemopathies. It also shows that it is possible to prove the independent nature of the two tumor clones, thus allowing optimized therapeutic management. |
| Databáze: | OpenAIRE |
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