Prognostic impact of standardized uptake value of F-18 FDG PET/CT in nasopharyngeal carcinoma
| Autor: | Pek-Lan Khong, Bingsheng Huang, Winnie K.S. Chan, David W.C. Yeung, Dora L.W. Kwong |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Standardized uptake value Multimodal Imaging Disease-Free Survival Fluorodeoxyglucose F18 Carcinoma medicine Humans Radiology Nuclear Medicine and imaging Aged Proportional Hazards Models PET-CT Nasopharyngeal Carcinoma medicine.diagnostic_test Proportional hazards model business.industry Nasopharyngeal Neoplasms General Medicine Middle Aged Reference Standards medicine.disease Prognosis Primary tumor stomatognathic diseases medicine.anatomical_structure Nasopharyngeal carcinoma Positron emission tomography Cervical lymph nodes Positron-Emission Tomography Multivariate Analysis Female Radiology business Nuclear medicine Tomography X-Ray Computed |
| Zdroj: | Clinical nuclear medicine. 36(11) |
| ISSN: | 1536-0229 |
| Popis: | PURPOSE We evaluated the use of metabolic parameters of F-18 fluorodeoxyglucose positron emission tomography (FDG PET) for the assessment of the primary tumor and nodal metastasis in predicting survival in nasopharyngeal carcinoma (NPC) patients. MATERIALS AND METHODS The F-18 FDG PET/CT (computed tomography) scans of 46 consecutive newly diagnosed NPC patients were retrospectively reviewed. Maximal standardized uptake value (SUVmax) corrected for lean body mass of primary tumor (pSUVmax) and highest SUVmax of cervical lymph nodes (nSUVmax) were recorded. The association of FDG uptake and 2-year disease-free survival (DFS) was examined. RESULTS Significantly better DFS was found in patients with pSUVmax |
| Databáze: | OpenAIRE |
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