Pharmacokinetics in plasma and alveolar regions of a healthy calf intramuscularly administered a single dose of orbifloxacin
Autor: | Tetsuro, Kuramae, Shingo, Ishikawa, Aki, Kono, Seiji, Hobo |
---|---|
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Journal of Veterinary Medical Science. 84:400-405 |
ISSN: | 1347-7439 0916-7250 |
Popis: | This study analyzed the pharmacokinetics of orbifloxacin (OBFX) in plasma, and its migration and retention in epithelial lining fluid (ELF) and alveolar cells within the bronchoalveolar lavage fluid (BALF). Four healthy calves received a single dose of OBFX (5.0 mg/kg) intramuscularly. Post-administration OBFX dynamics were in accordance with a non-compartment model, including the absorption phase. The maximum concentration (C |
Databáze: | OpenAIRE |
Externí odkaz: |