A Case Series of Five People Living with HIV Hospitalized with COVID-19 in Chicago, Illinois

Autor: Natasha N Pettit, Christopher C. Frohne, Jina Saltzman, Mai T. Pho, Aniruddha Hazra, Jessica Schmitt, Kenneth Pursell, Jessica P Ridgway, Arno Uvin, Moira McNulty, Jean Luc Benoit, David Pitrak, Brianna Farley
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Pediatrics
medicine.medical_specialty
medicine.medical_treatment
Pneumonia
Viral
HIV Infections
Azithromycin
03 medical and health sciences
Betacoronavirus
0302 clinical medicine
Antiretroviral Therapy
Highly Active
Pandemic
medicine
Humans
Serologic Tests
030212 general & internal medicine
Pandemics
Retrospective Studies
Mechanical ventilation
Chicago
030505 public health
business.industry
SARS-CoV-2
Clinical and Epidemiologic Research
Public Health
Environmental and Occupational Health
COVID-19
Retrospective cohort study
Hydroxychloroquine
Middle Aged
medicine.disease
CD4 Lymphocyte Count
Cephalosporins
COVID-19 Drug Treatment
Diarrhea
Treatment Outcome
Infectious Diseases
Coinfection
Female
medicine.symptom
0305 other medical science
business
Coronavirus Infections
Viral load
medicine.drug
Zdroj: AIDS Patient Care and STDs
AIDS Patient Care STDS
ISSN: 1557-7449
1087-2914
DOI: 10.1089/apc.2020.0103
Popis: The risk of COVID-19 among people living with HIV (PLWH) is largely unknown and there have been very few reported cases in the literature. We report a case series of five PLWH with COVID-19. We identified all patients with a diagnosis of HIV who tested positive for SARS-CoV-2 at University of Chicago Medicine between March 1, 2020, and April 7, 2020. We retrospectively collected data regarding demographics, comorbidities, medications, laboratory test results, radiology results, and outcomes associated with COVID-19. All five PLWH with COVID-19 were African American; 80% (4/5) were cisgender females. The mean age of patients was 48 years old (range 38–53). The majority of patients presented with cough, fever, and shortness of breath. Three patients had diarrhea. One patient presented with predominantly cardiac symptoms. All were taking antiretroviral therapy (ART) with CD4 count >200 cells/mm(3) and suppressed HIV viral loads at the time of COVID-19 diagnosis. All five patients were hospitalized, two required supplemental oxygen, and none required mechanical ventilation. Four patients were treated with azithromycin and a cephalosporin and two were also treated with hydroxychloroquine. The median length of stay was 3 days (range 2–7). All patients recovered. More research is needed to understand the risks of COVID-19 among PLWH and the impact of ART on outcomes for patients with COVID-19.
Databáze: OpenAIRE
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