A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning
| Autor: | Masao Murakami, Paul R. Bolton, Toshiki Tajima, Mitsuru Yamagiwa, Hiroki Shirato, Kenneth Sutherland, Masayori Ishikawa, Satoshi Miyajima, Hiroyuki Date |
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| Rok vydání: | 2009 |
| Předmět: |
Organs at Risk
Materials science Proton Gaussian Physics::Medical Physics Ocular Melanoma Monte Carlo method Physical Therapy Sports Therapy and Rehabilitation Radiation Dosage laser acceleration Spectral line symbols.namesake Optics Proton Therapy Humans Radiology Nuclear Medicine and imaging ocular melanoma Melanoma Proton therapy Monte Carlo simulation Radiation business.industry Eye Neoplasms Lasers Radiotherapy Dosage General Medicine Tumor Burden symbols business Monte Carlo Method Energy (signal processing) Beam (structure) |
| Zdroj: | Radiological Physics and Technology. 3:16-22 |
| ISSN: | 1865-0341 1865-0333 |
| DOI: | 10.1007/s12194-009-0071-4 |
| Popis: | The results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot scanning method utilizing active energy modulation, which also minimizes the number of target spots was developed. We simulated various parameter values for the particle energy spread and the pencil beam diameter in order to determine values suitable for medical treatment. We found that a 2.5-mm-diameter proton beam with a 5% Gaussian energy spread was suitable for treatment of ocular melanoma while preserving vision for the typical case that we simulated. The energy spectra and the required proton current were also calculated and are reported. The results are intended to serve as a guideline for a new class of low-cost, compact accelerators. |
| Databáze: | OpenAIRE |
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